L-citrulline: Benefits, Uses and Dosage

L-citrulline: Benefits, Uses and Dosage | Leopard Nutrition

If you're into fitness, you've probably heard about L-citrulline. This amino acid is known for its benefits to the bodybuilder and fitness freaks alike.

Here, we'll take a look at what L-citrulline is, what its benefits are, and how you can use it to improve your health and workouts.

Spoiler alert: dosage is key! Let's get started.

1. What is L-citrulline?
2. What are its benefits?
3. How does L-citrulline work in the body and what are its uses?
4. What is the recommended dosage for L-citrulline supplements?
5. Are there any side effects associated with taking L-citrulline supplements?
6. How does L-citrulline interact with other substances, including food and drugs?
6. How can you include more L-citrulline in your diet to enjoy its benefit?

What is L-citrulline?

L-citrulline is an amino acid that plays an important role in the body's urea cycle, which helps to remove toxins from the blood. L-citrulline is found naturally in watermelons, and it can also be made in the laboratory.

L-citrulline supplements are often used to boost exercise performance, as they can increase levels of L-arginine and L-ornithine in the body. In addition, L-citrulline has been shown to increase levels of ATP, the energy molecule that fuels muscle contraction.

L-citrulline is also used to treat certain medical conditions, such as erectile dysfunction and high blood pressure. L-citrulline supplements are generally safe, but they can cause side effects such as stomach upset and diarrhea.

What are its benefits?

L-citrulline is an amino acid that occurs naturally in watermelons and other cucurbit fruits. It has a number of potential health benefits, including improved circulation, reduced blood pressure, and enhanced exercise performance.

L-citrulline supplements are often used to treat erectile dysfunction and other circulatory disorders. Additionally, citrulline may also be effective in treating other conditions like fatigue, muscle soreness, and diabetes.

While more research is needed to confirm the efficacy of L-citrulline supplements, they are generally safe and well-tolerated.

Therefore, L-citrulline may be worth considering for those looking to improve their overall health and well-being.

How does L-citrulline work in the body and what are its uses?

L-citrulline is involved in a number of important biochemical reactions in the body.

One of its main functions is to serve as a precursor for the production of nitric oxide, which is a gas that plays an important role in regulating blood pressure and blood flow. L-citrulline also helps to remove toxins from the liver and improve kidney function.

In addition, citrulline has been shown to boost exercise performance and protect against exercise-induced damage to muscles. As a result, citrulline supplements are often used by athletes to improve their performance and reduce recovery time.

Citrulline supplements are also popular among people who want to improve their overall health and well-being.

Uses Of L-citrulline

Here are some of the uses of L-citrulline:

  1. Citrulline is used for heart disease, chest pain (angina), high blood pressure, erectile dysfunction (ED), and improving athletic performance.
  2. It is also used for Alzheimer's disease, dementia, fatigue, muscle weakness, sickle cell disease, diabetes, high cholesterol, and citrulline deficiency.
  3. Citrulline is sometimes taken by mouth for reducing symptoms of early Parkinson's disease. Early research shows that citrulline might improve movements and daily living activities in people with early Parkinson's disease.
  4. Some people apply citrulline to the skin for wounds and skin ulcers.


Note: L-citrulline should not be used in place of prescription medications for any of the above conditions. Citrulline is possibly effective in treating some of these medical conditions.

What is the recommended dosage for L-citrulline supplements?

The recommended dosage of citrulline supplements varies depending on the person's age, weight, and fitness level.

  • For adults, the recommended dosage is 3-6 grams per day.
  • For children, the dosage should be adjusted based on weight. For example, a child weighing 50 pounds would need 2 grams of citrulline per day.

Are there any side effects associated with taking L-citrulline supplements?

Citrulline supplements are generally safe and well-tolerated, but mild side effects such as stomach upset and diarrhea have been reported.

As with any dietary supplement, it is important to speak with a healthcare provider before taking citrulline to ensure it is safe for you.

L-citrulline interaction with other substances, including food and drugs

L-citrulline is converted into L-arginine in the body, which then interacts with other substances, including food and drugs.

L-arginine is known to interact with medications for high blood pressure and heart conditions. Therefore, it is important to speak with a healthcare provider before taking L- citrulline supplements if you are taking any medications.

L- citrulline may also interact with certain foods, such as those high in protein or copper. When taken with protein-rich foods, L- citrulline can increase the amount of time it takes for the body to break down the protein.

Copper-rich foods can inhibit the absorption of L- citrulline. Therefore, it is best to take L- citrulline on an empty stomach or at least two hours after eating a meal.

How can you include more L-citrulline in your diet to enjoy its benefits?

While citrulline is available in supplement form, the best way to enjoy its benefits is to include it in your diet.

Watermelon is the richest natural source of citrulline, so eating this juicy fruit on a regular basis is a great way to improve your health. You can also find citrulline in other foods such as cucumbers, tomatoes, and squash.

So next time you're looking for a healthy snack, reach for a watermelon or cucumber instead of a bag of chips. Your body will thank you for it!

The  Takeaway

L-citrulline is a type of amino acid that is found in watermelon. It has many benefits, including improved circulation, reduced muscle soreness and better absorption of nutrients.

L-citrulline supplements can be taken to improve health and athletic performance. The recommended dosage for L-citrulline supplements is 1,000 mg per day. There are no known side effects associated with taking L-citrulline supplements, but it is always best to speak with a doctor before starting any new supplement regimen.

L-citrulline interacts with other substances, including food and drugs, so it is important to consult with a healthcare professional before taking it if you are on any medications or have any medical

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